Vinca Rosea waxay soo saartaa Vincristine
Vinca Rosea Extract Vincristine waxaa loola jeedaa xarunta dawooyinka ee Vincristine, kaas oo ka soo jeeda geedka periwinkle (Vinca rosea), kaas oo sidoo kale loo yaqaan Catharanthus roseus, indhaha dhalaalaya, Cape periwinkle, warshad xabaalaha, Madagascar periwinkle, gabadh jir ah, periwinkle casaan, Rose. periwinkle, waa nooc ka mid ah dhirta ubaxa ee qoyska Apocynaceae.
Vincristine waa alkaloid-dabiiciga ah waxaana loo isticmaalaa daawa kemotherabi si loogu daweeyo noocyada kala duwan ee kansarka, oo ay ku jiraan leukemia, lymphoma, iyo burooyinka adag.Waxay ka shaqeysaa carqaladeynta koritaanka unugyada kansarka.
| Walxaha firfircoon ee Shiineeska ah | Magaca Ingiriisiga | CAS Maya. | Miisaanka Molecular | Qaanuunka molecular |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | Catharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Oleanolic acid | 508-02-1 | 456.7 | C30H48O3 |
| QEEXIDDA Alaabada | ||
| Magaca Alaabta: | Vinca rosea asal ahaan | |
| Magaca Botanic: | Catharanthus roseus (L.) | |
| Qayb ka mid ah dhirta | Ubax | |
| Dalka Asal ahaan: | Shiinaha | |
| WAXYAABAHA FALANQAYNTA | QAABKA | Habka tijaabada |
| Muuqashada | budo fiican | Organoleptic |
| Midabka | budo fiican oo bunni ah | Muuqaal |
| Urta & Dhadhanka | Sifada | Organoleptic |
| Aqoonsiga | La mid ah muunadda RS | HPTLC |
| Soo Saarida Saamiga | 4:1-20:1;Vincristine 98% min | |
| Falanqaynta Sieve | 100% ilaa 80 mesh | USP39 <786> |
| Luminta qalajinta | ≤ 5.0% | Eur.Ph.9.0 [2.5.12] |
| Wadarta Dambas | ≤ 5.0% | Eur.Ph.9.0 [2.4.16] |
| hogaanka (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium(Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Meerkuri (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Bir culus | ≤ 10.0 mg/kg | Eur.Ph.9.0<2.4.8> |
| Haraaga dareeraha | U hoggaansan Eur.ph.9.0 <5,4> iyo EC Dardaaranka Yurub 2009/32 | Eur.Ph.9.0<2.4.24> |
| Hadhaaga sunta cayayaanka | U hoggaansanaanta Xeerarka (EC) No.396/2005 oo ay ku jiraan lifaaqyo iyo cusbooneysiin xiriir ah Reg.2008/839/CE | Chromatography gaaska |
| Bakteeriyada Aerobic (TAMC) | ≤10000 cfu/g | USP39 <61> |
| Khamiirka/Molds (TAMC) | ≤1000 cfu/g | USP39 <61> |
| Cudurka Escherichia coli: | Maqan 1g | USP39 <62> |
| Salmonella spp: | Maqan 25g | USP39 <62> |
| Staphylococcus aureus: | Maqan 1g | |
| Listeria monocytogenes | Maqan 25g | |
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
Astaamaha sheyga ee Vinca Rosea Extract Vincristine waxaa ka mid noqon kara:
Nadiifin sare:Badeecadaha Vincristine sida caadiga ah waxay leeyihiin nadiif sare waxayna u hoggaansamaan heerarka adag ee soo saarista daroogada si loo hubiyo nadiifnimada iyo xasilloonida daawada.
Raadinta isha:Vincristine waxaa badanaa laga soo saaraa geedka Catharanthus roseus.Nidaamkeeda wax-soo-saarkeedu waa la raad-raaci karaa oo waafaqayaa ururinta iyo qeexidda wax-soo-saarka agabka dawada dhirta.
Degganaanshaha kiimikada:Sida xarun alkaloid ah, vincristine waxay leedahay xasillooni kiimiko oo wanaagsan waxayna ku habboon tahay wax soo saarka daawada iyo kaydinta muddada dheer.
Dhaqdhaqaaqa ka hortagga burooyinka:Sida daawada ka hortagga burooyinka, vincristine waxay leedahay waxqabad lagu xakameynayo koritaanka iyo faafidda unugyada burooyinka waxayna ku habboon tahay daaweynta kansarrada kala duwan.
Xaqiijinta caafimaad:Vincristine si caafimaad leh ayaa loo xaqiijiyay waxaana si weyn loogu isticmaalaa waxqabadka caafimaadka, iyada oo la isku halayn karo taageerada xogta saamaynta dawooyinka iyo daaweynta.
Sifooyinkan alaabtu waxay muujinayaan tayada, dhaqdhaqaaqa, iyo qiimaha kiliinikada ee vincristine oo ah dawo muhiim ah oo ka hortagga kansarka.
Vinca Rosea Extract Vincristine waxaa ugu horayn caan ku ah codsiyadeeda dawooyinka ee daawaynta kansarka oo aan caadi ahaan lala xidhiidhin faa'iidooyinka caafimaad ee tooska ah ee isticmaalka guud ee macaamiisha.Vincristine, oo laga soo qaatay geedka Vinca rosea, waa dawo dawayn kemoterabi oo awood leh oo loo isticmaalo daawaynta noocyada kala duwan ee kansarka, oo ay ku jiraan leukemia, lymphoma, iyo burooyinka adag.Waxay ka shaqeysaa faragelinta koritaanka unugyada kansarka.
Waxaa muhiim ah in la ogaado in Vincristine ay tahay dawo la soo qoray oo lagu bixiyo kormeerka xirfadlayaasha daryeelka caafimaadka, isticmaalkeeduna wuxuu la xiriiraa waxyeellooyin iyo khataro ka iman kara.Sidaa darteed, sida caadiga ah looma suuq geeyo ama looma isticmaalo faa'iidooyinkeeda caafimaad ee ka baxsan goobaha caafimaadka.
Codsiyada faahfaahsan ee Vinca Rosea Extract Vincristine waxaa ka mid ah:
Daaweynta Kansarka:Vincristine waxaa inta badan loo isticmaalaa daawaynta noocyada kala duwan ee kansarka, oo ay ku jiraan leukemia, lymphoma, iyo burooyinka adag.Waxaa loo maamulaa qayb ka mid ah hababka daaweynta kiimoterabiga si loo joojiyo koritaanka unugyada kansarka.
Cilmi-baarista Dawooyinka:Soosaarku waxa loo adeegsadaa cilmi-baadhista dawooyinka ee horumarinta daawaynta cusub ee kansarka iyo daraasadda hab-dhaqankeeda.
Kiimikada Daawada:Vincristine waxay u adeegtaa sidii xarun qiimo leh oo ku taal berrinkii kimisteriga daawada, ka qayb qaadashada horumarinta daawooyinka cusub iyo wakiilada daweynta.
Bayoolaji:Soosaarku waxa laga yaabaa in lagu shaqeeyo codsiyada tignoolajiyada noolaha, sida soo saarista hababka ka hortagga kansarka iyo hababka gudbinta daroogada.
Tijaabooyin Caafimaad:Vincristine waxay ku lug leedahay tijaabooyin caafimaad si ay u sahamiso waxtarkeeda daaweynta noocyada kala duwan ee kansarka iyo inay baarto codsiyada suurtagalka ah ee xaaladaha kale ee caafimaadka.
Samaynta Dawooyinka:Soosaarku waxa loo isticmaalaa samaynta alaabta dawooyinka, oo ay ku jiraan xalalka la isku duro iyo qaababka kale ee qiyaasta daaweynta kansarka.
Codsiyadani waxay muujinayaan isticmaalka kala duwan ee Vinca Rosea Extract Vincristine ee daaweynta kansarka, cilmi-baarista dawooyinka, iyo horumarinta daroogada.
Vincristine waa daawo kemotherabi oo awood leh, isticmaalkeedana waxaa lala xiriirin karaa waxyeelooyin dhowr ah oo suurtagal ah.Qaar ka mid ah dhibaatooyinka soo raaca ee budada Vincristine waxaa ka mid noqon kara:
Neurotoxicity:Vincristine waxay dhaawac u geysan kartaa habdhiska dareenka, taasoo keenta calaamado ay ka mid yihiin kabuubyo, xiirid, iyo daciifnimo xagga cirifka.
Saamaynta Caloosha:Dhibaatooyinka caadiga ah ee caloosha iyo mindhicirka waxaa ka mid noqon kara lallabbo, matag, calool-istaag, iyo calool xanuun.
Cadaadiska Dhuuxa Lafta:Vincristine wuxuu xakameyn karaa dhuuxa lafta, taasoo keenta hoos u dhaca wax soo saarka unugyada dhiigga, taas oo keeni karta dhiig-yaraan, korodhka u nuglaanshaha caabuqyada, iyo dhiig-baxa.
Timaha oo daata:Shakhsiyaadka qaarkood ayaa laga yaabaa inay dareemaan inay timo daataan ama timaha oo dhuuban taasoo ka dhalatay daawaynta Vincristine.
Daanka Xanuunka:Vincristine waxay keeni kartaa nooc gaar ah oo xanuun ah oo loo yaqaan "vincristine-induced neuropathy-acute-onset," kaas oo lagu garto xanuunka daanka iyo liqitaanka oo ku adag.
Saamaynta kale ee suurtagalka ah:Waxyeellooyinka dheeraadka ah waxaa ka mid noqon kara daciifnimada murqaha, isbeddelka cadaadiska dhiigga, iyo falcelinta xasaasiyadda.
Waxaa muhiim ah in la ogaado in liiska kore uusan ahayn mid dhameystiran, xirfadlayaasha daryeelka caafimaadkuna waa inay si dhow ula socdaan shakhsiyaadka qaata Vincristine waxyeellooyin kasta oo suurtagal ah.Waxyeellooyinka gaarka ah iyo darnaantoodu way ku kala duwanaan karaan qof ilaa qof.Bukaan-socodka waa in ay kala hadlaan saameynaha soo raaca iyo walaacyada ay ka qabaan daryeelkooda caafimaad ka hor inta aysan bilaabin daaweynta Vincristine.
Baakadaha iyo Adeegga
Baakadaha
* Waqtiga gaarsiinta: Qiyaastii 3-5 maalmood oo shaqo kadib lacag bixintaada.
* Xidhmada: Ku jira durbaannada fiber-ka oo ay ku jiraan laba bac oo balaastig ah.
* Miisaanka saafiga ah: 25kgs/ durbaan, Miisaanka Guud: 28kgs/Drum
* Cabbirka durbaanka & mugga: ID42cm × H52cm, 0.08 m³/ durbaan
* Kaydinta: Waxaa lagu kaydiyaa meel qalalan oo qabow, ka fogow iftiinka xooggan iyo kulaylka.
* Nolosha shelf: Laba sano marka si habboon loo kaydiyo.
Raridda
* DHL Express, FEDEX, iyo EMS ee tiro ka yar 50KG, oo inta badan loo yaqaan adeegga DDU.
* Maraakiibta badda ee tiro ka badan 500 kg;iyo dhoofinta hawada 50 kg ee kor ku xusan.
* Alaabooyinka qiimaha sare leh, fadlan dooro rarida hawada iyo muujinta DHL ee badbaadada.
* Fadlan xaqiiji haddii aad ogolaan karto marka alaabtu gaadho kastamkaaga ka hor intaadan dalban.Iibsadayaasha ka yimid Mexico, Turkey, Italy, Romania, Russia, iyo meelaha kale ee fogfog.
Hababka Lacag-bixinta iyo Bixinta
Express
Ka yar 100kg, 3-5 maalmood
Adeegga albaab ilaa albaab si fudud alaabta looga soo qaadan karo
By Badda
In ka badan 300kg, Qiyaastii 30 maalmood
Dekadda ilaa iyo dakadda waxa loo baahan yahay dilaaliinta nadiifinta xirfada leh
By Hawada
100kg-1000kg, 5-7 maalmood
Gegida dayuuradaha ilaa madaarka dallaalka nadiifinta xirfadlayaasha ah ayaa loo baahan yahay
Faahfaahinta Wax-soo-saarka (Jaantuska Socodka)
1. Wax-soo-saarka iyo Goynta
2. Soo saarid
3. Isku-duubni iyo Nadiifin
4. Qalajinta
5. Habaynta
6. Xakamaynta tayada
7. Baakadaha 8. Qaybinta
Shahaado
It waxaa shahaado siisay shahaadooyin ISO, HALAL, iyo KOSHER.
