Soosaarka Vinca Rosea Vincristine
Vinca Rosea Extract Vincristine waxaa loola jeedaa isku-darka daawada Vincristine, kaas oo laga soo qaatay geedka periwinkle (Vinca rosea), kaas oo sidoo kale loo yaqaan Catharanthus roseus, indhaha dhalaalaya, Cape periwinkle, geedka qabriga, Madagascar periwinkle, gabdh gabowday, casaan periwinkle, rose periwinkle, waa nooc ubaxeed oo waara oo ku jira qoyska Apocynaceae.
Vincristine waa alkaloid dabiici ah waxaana loo isticmaalaa daawo kiimoterabiga ah si loogu daaweeyo noocyo kala duwan oo kansar ah, oo ay ku jiraan leukemia, lymphoma, iyo burooyinka adag. Waxay ka shaqeysaa carqaladeynta koritaanka unugyada kansarka.
| Waxyaabaha ugu Muhiimsan ee Firfircoon ee Shiinaha | Magaca Ingiriisiga | Lambarka CAS. | Miisaanka Molekulerka | Qaacidda Molekuleerigga |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstoneine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2(C4H6O6);C |
| 长春瑞滨 | Vinorelbin | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | Catharanthin | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β-谷甾醇 | β-Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Aashitada oleanolic | 508-02-1 | 456.7 | C30H48O3 |
| QIIMEYNTA ALAABTA | ||
| Magaca Badeecada: | Vinca rosea laga soo saaray | |
| Magaca Dhirta: | Catharanthus roseus (L.) | |
| Qayb ka mid ah geedka | Ubax | |
| Dalka Asalka: | Shiinaha | |
| ALAABADA FALANQAYNTA | QEEXIDDA | HABKA IMTIXAANKA |
| Muuqaalka | Budada fiican | Organoleptic |
| Midab | Budada buniga ah ee khafiifka ah | Muuqaal |
| Ur iyo Dhadhan | Sifo | Organoleptic |
| Aqoonsiga | La mid ah muunadda RS | HPTLC |
| Saamiga Soosaarka | 4:1~20:1; Vincristine 98%daqiiqo | |
| Falanqaynta Shaandhada | 100% ilaa 80 mesh | USP39 <786> |
| Lumis marka la qalajiyo | ≤ 5.0% | Yuuro.Ph.9.0 [2.5.12] |
| Dambas Dhammaad ah | ≤ 5.0% | Yuuro.Ph.9.0 [2.4.16] |
| Rasaasta (Pb) | ≤ 3.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Arsenic (As) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Cadmium (Cd) | ≤ 1.0 mg/kg | Eur.Ph.9.0<2.2.58>ICP-MS |
| Meerkuriga (Hg) | ≤ 0.1 mg/kg -Reg.EC629/2008 | Eur.Ph.9.0<2.2.58>ICP-MS |
| Bir culus | ≤ 10.0 mg/kg | Yuuro.Ph.9.0 <2.4.8> |
| Haraaga dareeraha | U hoggaansan Eur.ph. 9.0 <5,4 > iyo Tilmaamaha Yurub ee EC 2009/32 | Yuuro.Ph.9.0 <2.4.24> |
| Haraaga Cayayaanka | Xeerarka u Hoggaansan (EC) No.396/2005 oo ay ku jiraan lifaaqyada iyo cusbooneysiinta is daba jooga Diiwaanka 2008/839/CE | Karoomatography Gaaska |
| Bakteeriyada hawada ku shaqeysa (TAMC) | ≤10000 cfu/g | USP39 <61> |
| Khamiirka/Caaryada (TAMC) | ≤1000 cfu/g | USP39 <61> |
| Escherichia coli: | Maqna 1g | USP39 <62> |
| bakteeriyada Salmonella: | Ma jiro 25g | USP39 <62> |
| Staphylococcus aureus: | Maqna 1g | |
| Listeria Monocytogenens | Ma jiro 25g | |
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxins ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
Astaamaha badeecada ee Vinca Rosea Extract Vincristine waxaa ka mid noqon kara:
Daahirnimo sare:Badeecadaha Vincristine badanaa waxay leeyihiin nadiifnimo sare waxayna u hoggaansamaan heerarka adag ee soo saarista daawada si loo hubiyo daahirnimada iyo xasilloonida daawada.
Raad-raaca isha:Vincristine waxaa badanaa laga soo saaraa geedka Catharanthus roseus. Habka wax soo saarkiisa waa la raadraaci karaa wuxuuna waafaqsan yahay qeexitaannada ururinta iyo soo saarista agabka daawada dhirta.
Xasiloonida kiimikada:Maadaama uu yahay isku-darka alkaloid, vincristine wuxuu leeyahay xasillooni kiimiko oo wanaagsan wuxuuna ku habboon yahay soo saarista daawooyinka iyo kaydinta muddada dheer.
Waxqabadka ka hortagga burooyinka:Maadaama uu yahay daawo ka hortagta burooyinka, vincristine wuxuu leeyahay firfircooni uu ku joojinayo koritaanka iyo faafitaanka unugyada burooyinka wuxuuna ku habboon yahay daaweynta kansarrada kala duwan.
Xaqiijinta kiliinikada:Vincristine si kiliinik ah ayaa loo xaqiijiyay waxaana si weyn loogu isticmaalaa dhaqanka caafimaadka, iyadoo la adeegsanayo taageero xog ah oo lagu kalsoonaan karo oo ku saabsan saameynta daawada iyo saameynta caafimaad.
Astaamaha badeecadani waxay muujinayaan tayada, dhaqdhaqaaqa, iyo qiimaha caafimaad ee vincristine oo ah daawo muhiim u ah ka hortagga kansarka.
Vinca Rosea Extract Vincristine waxaa si weyn loogu yaqaanaa isticmaalka dawooyinka ee daaweynta kansarka mana aha mid si toos ah ula xiriirta faa'iidooyinka caafimaad ee guud ahaan loo isticmaalo macaamiisha. Vincristine, oo laga soo qaatay geedka Vinca rosea, waa daawo kiimiko ah oo awood leh oo loo isticmaalo daaweynta noocyada kala duwan ee kansarka, oo ay ku jiraan leukemia, lymphoma, iyo burooyinka adag. Waxay ka shaqeysaa faragelinta koritaanka unugyada kansarka.
Waa muhiim in la ogaado in Vincristine uu yahay daawo dhakhtar qoray oo ay kormeerayaan xirfadlayaasha daryeelka caafimaadka, isticmaalkeeduna uu la xiriiro waxyeellooyin iyo khataro suurtagal ah. Sidaa darteed, badanaa looma suuq geeyo ama looma isticmaalo faa'iidooyinkeeda caafimaad marka laga reebo goobaha caafimaadka.
Isticmaalka faahfaahsan ee Vinca Rosea Extract Vincristine waxaa ka mid ah:
Daaweynta Kansarka:Vincristine waxaa inta badan loo isticmaalaa daawaynta noocyada kala duwan ee kansarka, oo ay ku jiraan leukemia, lymphoma, iyo burooyinka adag. Waxaa loo qaataa qayb ka mid ah hababka kiimoterabiga si loo joojiyo koritaanka unugyada kansarka.
Cilmi-baarista Daawada:Soosaarka waxaa loo isticmaalaa cilmi-baarista dawooyinka si loo horumariyo daaweynta kansarka cusub iyo daraasadda habka ficilkiisa.
Kiimikada Daawada:Vincristine wuxuu u adeegaa sidii isku-dhaf qiimo leh oo ku saabsan kiimikada daawada, isagoo gacan ka geysanaya horumarinta daawooyinka cusub iyo wakiilada daaweynta.
Bayoteknoolajiyadda:Soosaarka waxaa loo isticmaali karaa codsiyada bayoteknoolajiyada, sida soo saarista qaacidooyinka ka hortagga kansarka iyo nidaamyada keenista daawada.
Tijaabooyinka Caafimaadka:Vincristine waxay ku lug leedahay tijaabooyin caafimaad si loo sahamiyo waxtarkeeda daaweynta noocyada kala duwan ee kansarka iyo in la baaro codsiyada suurtagalka ah ee xaaladaha kale ee caafimaad.
Qaacidada Daawada:Soosaarka waxaa loo isticmaalaa diyaarinta alaabada dawooyinka, oo ay ku jiraan xalalka la isku duro iyo qaababka kale ee qiyaasta daaweynta kansarka.
Codsiyadani waxay muujinayaan isticmaalka kala duwan ee Vinca Rosea Extract Vincristine ee daaweynta kansarka, cilmi-baarista dawooyinka, iyo horumarinta daawada.
Vincristine waa daawo kiimiko oo awood leh, isticmaalkeeduna wuxuu la xiriiri karaa dhowr waxyeellooyin oo suurtagal ah. Qaar ka mid ah waxyeellooyinka suurtagalka ah ee budada Vincristine waxaa ka mid noqon kara:
Sunta neerfaha:Vincristine wuxuu waxyeello u geysan karaa habdhiska neerfaha ee durugsan, taasoo keenta calaamado sida kabuubyo, xanxanto, iyo daciifnimo ku timaadda addimada.
Saamaynta Xiidmaha Caloosha:Waxyeellooyinka caadiga ah ee caloosha iyo mindhicirka waxaa ka mid noqon kara lallabbo, matag, calool istaag, iyo xanuun caloosha ah.
Xakamaynta Dhuuxa Lafaha:Vincristine wuxuu xakameyn karaa dhuuxa lafaha, taasoo horseedaysa hoos u dhac ku yimaada wax soo saarka unugyada dhiigga, taasoo keeni karta dhiig la'aan, u nuglaanshaha caabuqyada oo kordha, iyo u janjeera dhiigbaxa.
Timaha oo daata:Dadka qaar ayaa laga yaabaa inay timaha daataan ama khafiifiyaan ka dib daaweynta Vincristine.
Xanuunka Daanka:Vincristine wuxuu sababi karaa nooc gaar ah oo xanuun ah oo loo yaqaan "vincristine-induced neuropathy-acute-onset," kaas oo lagu garto xanuunka daanka iyo dhibka liqidda.
Saameynaha Kale ee Suurtagalka ah:Waxyeellooyinka dheeraadka ah waxaa ka mid noqon kara daciifnimo muruqa ah, isbeddellada cadaadiska dhiigga, iyo falcelinta xasaasiyadda.
Waa muhiim in la ogaado in liiska kor ku xusan uusan ahayn mid dhammaystiran, xirfadlayaasha daryeelka caafimaadkuna waa inay si dhow ula socdaan shakhsiyaadka qaadanaya Vincristine si ay u ogaadaan waxyeellooyinka iman kara. Waxyeellooyinka gaarka ah iyo darnaantoodu way kala duwanaan karaan qof ilaa qof. Bukaannadu waa inay kala hadlaan waxyeellooyinka iman kara iyo walaacyada bixiyaha daryeelka caafimaad ka hor inta aysan bilaabin daaweynta Vincristine.
Baakadeynta iyo Adeegga
Baakad
* Waqtiga Bixinta: Qiyaastii 3-5 maalmood oo shaqo ka dib lacagtaada.
* Xidhmo: Foornooyin faybar ah oo ay ku jiraan laba bac oo balaastig ah.
* Miisaanka saafiga ah: 25kgs/durbaanka, Miisaanka guud: 28kgs/durbaanka
* Cabbirka Durbaanka iyo Mugga: ID42cm × H52cm, 0.08 m³/ Durbaan
* Kaydinta: Ku kaydi meel qalalan oo qabow, ka fogow iftiinka iyo kulaylka xooggan.
* Muddada kaydinta: Laba sano marka si habboon loo kaydiyo.
rarida
* DHL Express, FEDEX, iyo EMS oo loogu talagalay tiro ka yar 50KG, oo badanaa loogu yeero adeegga DDU.
* Maraakiibta badda ee ka badan 500 kg; iyo maraakiibta cirka ayaa diyaar u ah 50 kg ee ka sarreeya.
* Wixii alaab qiimo sare leh, fadlan dooro rarida hawada iyo DHL express si aad u hesho badbaado.
* Fadlan xaqiiji haddii aad samayn karto oggolaanshaha marka alaabtu gaarto kastamkaaga ka hor intaadan dalban. Iibsadayaasha ka yimid Mexico, Turkiga, Talyaaniga, Romania, Ruushka, iyo meelaha kale ee fog.
Hababka Lacag-bixinta iyo Bixinta
Degdegga ah
Ka yar 100kg, 3-5 Maalmood
Adeegga albaabka ilaa albaabka oo si fudud loo soo qaadan karo alaabta
Badda agteeda
In ka badan 300kg, Qiyaastii 30 maalmood
Dalaal xirfadle ah oo adeegga dekedda ilaa dekedda ayaa loo baahan yahay
Hawada
100kg-1000kg, 5-7 Maalmood
Dalaal xirfadle ah oo adeegga garoonka diyaaradaha ilaa garoonka diyaaradaha ayaa loo baahan yahay
Faahfaahinta Wax Soo Saarka (Jaantuska Socodka)
1. Soo saarista iyo Goosashada
2. Soo saarista
3. Xoojinta iyo Nadiifinta
4. Qallajinta
5. Jaangooynta
6. Xakamaynta Tayada
7. Baakad 8. Qaybinta
Shahaadada
It waxaa shahaado ka haysta shahaadooyinka ISO, HALAL, iyo KOSHER.
