Budada Sinomenine Hydrochloride
Sinomenine Hydrochloride waa kiimiko ka samaysan warshadda Sinomenium acutum, taas oo inta badan laga helo Bariga Aasiya. Waa alkaloids dhaqan ahaan loo isticmaali jiray daawaynta Shiinaha si ay u ilaaliso caabuqa iyo xanuunka. Foomka hydrochloride waa milix kor u qaada milanka xarunta iyo xasilloonida, taasoo ka dhigaysa mid ku habboon isticmaalka dawooyinka.
Sinomenine Hydrochloride ayaa lagu bartay saameynteeda daweynta ee suurtagalka ah ee daaweynta xaaladaha sida rheumatoid arthritis-ka, sababtoo ah awoodda ay u leedahay in ay wax ka beddesho habka difaaca iyo yaraynta bararka. Waxay u shaqeysaa iyadoo la joojinayo soo saarista cytokines pro-inflammatory iyo dhexdhexaadiyeyaasha kale ee ku lug leh jawaab-celinta bararka.
Marka lagu daro saamaynta anti-bararka iyo xanuunka, Sinomenine Hydrochloride waxay sidoo kale muujisay suurtogalnimada neuroprotection, anti-fibrosis, iyo hawlaha ka hortagga burooyinka ee daraasado kala duwan oo hore.
Magaca rasmiga ah: (9a,13a,14a)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-hal, monohydrochloride
Lambarka CAS: 6080-33-7
Ereyada la midka ah: Cucoline NSC 76021
Foomamka Molecular: C19H23NO4 • HCl
Miisaanka Formula: 365.9
daahirnimo:≥98% A adag crystalline
Solubility(Baro Kala duwanaanshaha Solubility)
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 5 mg/ml
PBS (pH 7.2): 5 mg/ml
Asal ahaan: Plant/Sinomenium acutum
Dhoofinta & Macluumaadka Kaydinta:
Kaydinta -20°C
Raritaanka: Heerkulka qolka
Xasilooni: ≥ 4 sano
| Shayga | Tilmaamid | Natiijada |
| Assay (HPLC) | 98.0% | 98.12% |
| Muuqashada | Budada cad | U hogaansama |
| Cabbirka Qaybaha | 98% ilaa 80 mesh | U hogaansama |
| ur | Sifada | U hogaansama |
| Dhadhan | Sifada | U hogaansama |
| Astaamaha Jirka | ||
| Khasaare xagga qallajinta | ≤0.5% | 0.38% |
| Dambas | ≤0.5% | 0.46% |
| Biraha culus | ||
| Biraha culus (sida Pb) | Heerarka USP (<10ppm) | <10ppm |
| Arsenic (As) | ≤2pm | 0.78pm |
| hogaanka (Pb) | ≤2pm | 1.13pm |
| Cadmium(Cd) | ≤lppm | 0.36pm |
| Mercary(Hg) | ≤0.1pm | 0.01pm |
| Hadhaaga sunta cayayaanka | Aan la ogaan | Aan la ogaan |
| Wadarta PlateCount | NMT 10000cfu/g | 680 cfu/g |
| Wadarta khamiirka & caaryada | NMT 100cfu/g | 87 cfu/g |
| E.Coli | NMT 30cfu/g | 10 cfu/g |
| Salmonella | xun | xun |
| Gabagabo | Waafaqaya Heerka Ganacsiga | |
Saamaynta ugu weyn ee Sinomenine Hydrochloride waxaa ka mid ah:
(1) Ka-hortagga caabuqa: Waxay yaraysaa bararka.
(2) Kaalisyo: Waxay bixisa xanuunka dhimista.
(3) Immunosuppressive: Waxa ay joojisaa hawlaha hab-dhiska difaaca.
(4) Anti-rheumatic: Waxay daawaysaa rheumatoid arthritis-ka.
(5) Neuroprotective: Waxay ka ilaalisaa unugyada dareemayaasha dhaawaca.
(6) Anti-fibrotic: Waxay ka hortagtaa ama yaraysaa fibrosis nudaha.
Sinomenine Hydrochloride waxaa inta badan loo isticmaalaa meelaha soo socda:
(1) Rheumatology: Daawaynta rheumatoid arthritis-ka.
(2) Maareynta Xanuunka: Yaraynta xanuunka joogtada ah.
(3) Ka-hortagga caabuqa: Dhimista bararka.
(4) Immunomodulation: Habaynta habka difaaca jirka.
(5) Neuroprotection: Isticmaalka suurtagalka ah ee daaweynta neuroprotective.
Habka wax soo saarka ee Sinomenine Hydrochloride Powder waxaa lagu soo koobi karaa sida soo socota:
Diyaarinta Dhirta:Nadiifinta iyo qalajinta alaabta dhirta ceeriin.
Soo saarid:Isticmaalka dareerayaasha sida ethanol si loo soo saaro sinomenine ee alaabta dhirta.
Xoog-saarista:Uumi-baxa dareeraha si loo xoojiyo nuxurka sinomenine.
Alkalisation:Hagaajinta pH si loogu beddelo sinomenine qaabkeeda cusbada.
Soo saarista Dareeraha:Ku nadiifinta dareerayaasha organic sida anisole ama 1-heptanol.
Dhaqid:Biyo-dhaqashada biyaha si aad uga saarto wasakhda iyo raadadka dareeraha.
Aysiidh:Yaraynta pH si ay u soo dedejiso sinomenine hydrochloride.
Crystallization:Samaynta crystals of sinomenine hydrochloride.
Kala saarid:Centrifuging ama shaandhaynta si loo kala saaro crystals iyo xalka.
Qalajinta:Ka saaritaanka qoyaanka haraaga ah ee kiristaalo.
Milling:Ku shiididda kiristaalo engegan oo budo fiican ah.
Sifeynta:Hubinta qaybinta cabbirka walxaha isku midka ah.
Xakamaynta tayadaTijaabinta nadiifnimada, fiirsashada, iyo heerarka microbiological.
Baakad:Baakad nadiif ah oo sugan oo qaybinta.
Kaydinta: Ku hay meel qabow, qalalan, oo nadiif ah, Ka ilaali qoyaanka iyo iftiinka tooska ah.
Xidhmada badan: 25kg / durbaan.
Waqtiga Hogaaminta: 7 maalmood kadib dalabkaaga.
Nolosha shelf: 2 sano.
Fiiro gaar ah: Tilmaamaha gaarka ah sidoo kale waa la gaari karaa.
Express
Ka yar 100kg, 3-5 maalmood
Adeegga albaab ilaa albaab si fudud alaabta looga soo qaadan karo
By Badda
In ka badan 300kg, Qiyaastii 30 maalmood
Dekadda ilaa iyo dakadda waxa loo baahan yahay dilaaliinta nadiifinta xirfada leh
By Hawada
100kg-1000kg, 5-7 maalmood
Gegida dayuuradaha ilaa madaarka dallaalka nadiifinta xirfadlayaasha ah ayaa loo baahan yahay
Bioway Organic waxay heshay USDA iyo EU organic, BRC, ISO, HALAL, KOSHER, iyo shahaadooyin HACCP.
