Stephania ayaa ka soo baxa budada cepharanthine

Magaca badeecada: Stephania Japonica ayaa laga soo saaray
Latin ka soo jeeda: Stephania Cephallantha Harata Harata (Stephania Japonica (Thunb.
Muuqaalka: cad, budada cad ee cawlan
Qiyaasta Firfircoon: Ceepharanthine 80% -99% HPLC
Qeybta loo adeegsaday: tuber / xidid
Codsi: Alaabada daryeelka caafimaadka
Barta dhalaalaya: 145-155 °
Wareejin gaar ah: D20 + 277 ° (c = 2inchloform)
Point Point: 654.03 ° C (qiyaasta adag)
Cufnaanta: 1.1761 (qiyaasta adag)
Tilmaanta tabaruca ah: 1.5300 (qiyaasta)
Xaaladaha Kaydinta: Entrinetgas (nitrogen ama Argon) AT2-8 ° C
SOLUBENES: ku milma si sidaas (35mg / ml) ama ethanol (20mg / ml)
Canshting Coffient (PKA): 7.61 ± 0.20 (saadaaliyay)


Si faahfaafo

Macluumaadka kale

Calaamadaha wax soo saarka

Hordhaca Waxsoosaarka

Stephania Fist-ka budada Cepharanthine waa walax laga soo qaaday digriiga geedaha stephalantha Harata (Thunb Japonica) ama Stephania Epiganant loUNNANNENSIS YUNNANNSIS YUNNANNSIS. Ceepharanthine waa wax soo saar dabiici ah oo laga go'doomay geedkan oo uu ahaa mowduuca daraasado kala duwan ah sababtuna tahay suuragalnimada takoorista ee suurtagalka ah. Waxaa la ogaaday inay soo bandhigtay nashaadaadyo la-dagaallanka SARS-2, oo muujinaya wax ku oolnimada xakamaynta faafitaanka fayraska. Intaa waxaa sii dheer, Ceepharanthine waxay muujisay awoodda dib loogu beddelo P-glycopotein (PPP) iska caabbinta miyir-beelka ah ee unugyada qaarkood iyo kor u qaadista dareenka wakiilada anticulic-ka ee moodooyinka tijaabada ah. Intaa waxaa sii dheer, waxaa la muujiyey inay leedahay saameynta dhalmada ee beerka aadanaha ee Beerka Birtochrome P450 Enzymes Cypymes Cyp3A4, iyo Cyp2C9, iyo CYP2C9, iyo dhibaatooyinka ka hortagga, iyo dhibaatooyinka ka hortagga.
Marka la soo koobiyo, Stephania budada 'Clepharanthine' waa nooc budo ah oo ka mid ah shekharanthine-ka dabiiciga ah ee ka soo baxay 'cephalanthen cephalantha', kaas oo ka soo muuqday suurtagalnimada astimiyooyinka kala duwan ee dawooyinka.

Faahfaahin (COA)

Badeeco Cephalanthid
Sanduuq 481-49-2
Wax wax lugu dhasho 80% ~ 99%
Muuqashada Budada cad
Isku xiris 1kg / foil bacda
Wax Cayimid
Muuqashada budada cad ee cawlan, ur dhexdhexaad ah, sicir-barar aad u sarreeya
Aqoonsi TLC: xalka caadiga ah iyo xalka tijaabada isla isla meesha, ryf
Assy (si hufan) 98.0% - 102.0%
Gaar ah optical -2.4 ° ° ~ -2.8 °
PH 4.5 ~ 7.0
Biraha culus (sida pb) ≤0ppm
As ≤ppm
Pb ≤0.5ppm
Cd ≤ppm
Hg ≤0.1ppm
Walaxda laxiriira Ujeedka kama weyneyn booska xalka heerka caadiga ah
Haraaga haraaga ah <0.5%
Biyo ku jira <%

Astaamaha wax soo saarka

Stephania soosaarka bupharanthine waa badeecad dabiici ah oo laga soo qaatay geedka Stephaniya Cephalarantha Hacaa. Waxaa la ogaaday inay leedahay dhowr guri oo dawooyinka, oo ay ku jiraan:
1. Anti-SARS-Cov-2
2. Saamaynta xannibaadda lagu kordhiyo fayraska
3. Dib-u-noqoshada P-glycopotein-ka hooseeya iska caabin badan
4. Kordhinta xasaasiga ah wakiilada anticy
5. Saamaynta xannibaadda beerka ee beerka aadanaha cytochrome p450 enzymes Cyp3A4, Cyp2E1, iyo Cyp2c9
6. Ka hortagga ka hortagga, anti-bararka, iyo saamaynta ka hortagga

Waa maxay Bisynthesis ee Ceyphalanthine?

Biyosynthesis ee Ceyrtanthine ee Cepharanthie ee Stephania ayaa ku bilaabata uumiga Dopamine iyo 4-hydroxyphehehylacethehydehyde (4-HCSLAIENES SyntAse (NCS), oo dhalaya Norcoclaurine.

Waa maxay jilitaanka Ceepharanthine?

Ceepharanthine waxay ku milmaysaa xabagta dabiiciga ah sida ethanol, DMSO, iyo Dimithyl Mormside (DMF). Xoolaha Ceepharanthine ee xabaashu waa qiyaastii 2, 5, iyo 10 mg / ml, siday u kala horreeyaan. Ceepharanthine ayaa si aad ah u xajinaysa xaraashka aqueous.

Codsiyada

Warshadaha Codsiyada ee Stephania Powder Powder waxaa ka mid ah dawooyinka, nafaqada, cilmiga bayoolajiga, iyo daawada dhirta, codsiyada dhirta waa sida soo socota:
Isticmaalka suurtagalka ah ee daaweynta fayraska fayraska
Suurtogal ahaan sida xaqiijinta daaweynta ee kansarka
Awoodda loo adeegsado daaweynta ka hortagga bararka
Suurtogal ahaan sida wakiilka analgesic
Codsiyadan ayaa muujinaya adeegsiga suurtagalka ah ee suurta galka ah ee Stephania ka soo saaraan budada Cepharanthine xaaladaha daweynta kala duwan.


  • Hore:
  • Xiga:

  • Baakadaha iyo Adeegga

    Ka iibsi
    * Waqtiga gudbinta: Qiyaastii 3-5 maalmaha shaqada ka dib bixintaada.
    * Xidhmada: Drunts-ka fiber-ka leh laba bac oo caag ah gudaha.
    * Miisaanka saafiga ah: 25kgs / Drum, Miisaan culus: 28kgs / Drum
    * Crunt SULE & mugga: ID42CM × H52cm, 0.08 m³ / Drum
    * Kaydinta: lagu keydiyo meel qalalan oo qabow, ka fogow nalka adag iyo kuleylka.
    * Nolosha shelf: Laba sano markii si sax ah loo keydiyo.

    Maraakiibta
    * DHL Express, FedEx, iyo EMS tirada ka yar 50kg, waxaa badanaa loo yaqaan adeegga DDU.
    * Dhoofinta badda ee tirada ka badan 500 kg; Dhoofinta hawada waxaa laga heli karaa 50 kg kor ku xusan.
    * Alaabada qiimaha sare leh, fadlan xulo dhoofinta hawada iyo DHL Express ee badbaadada.
    * Fadlan xaqiiji haddii aad sameyn karto caddeynta marka alaabada ay gaarto caadooyinkaaga ka hor intaadan dalban amar. Iibsadayaasha ka socda Mexico, Turkey, Italy, Romania, Russia, iyo aagagga kale ee fog.

    Xirmooyinka bayooy ee soosaarka dhirta

    Bixinta iyo hababka gudbinta

    Muujin
    100kg, 3-5 maalmood
    Albaabka adeegga albaabka ayaa si fudud u soo qaadaya alaabada

    By badda
    In ka badan300kg, ku dhawaad ​​30 maalmood
    Dekadda loogu talagalay Diyaaradda Xirfadlaha Adeegga Dekadda ee loo baahan yahay

    Hawada
    100kg-1000kg, 5-7 maalmood
    Gegada Diyaaradaha ee Diyaaradda Aqalka Diyaaradaha ee Diyaaradda ayaa loo baahan yahay

    kala soocid

    Faahfaahinta Soo-Saarka (Qiyaasta qulqulka)

    1. Fadhig iyo goosashada
    2. Soo saarista
    3. U fiirsashada iyo nadiifinta
    4. Qalajinta
    5. Heerka
    6. Xakamaynta Tayada
    7. Baakadaha 8. Qaybinta

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