Waa maxay faa'iidooyinka ginsenosides?

Hordhac
Ginsenosideswaa nooc ka mid ah xeryahooda dabiiciga ah ee laga helo xididada geedka Panax ginseng, kaas oo qarniyo badan loo isticmaali jiray daawada dhaqameed ee Shiinaha. Xeryahooda bioactive-ka ah waxay heleen fiiro gaar ah sanadihii ugu dambeeyay sababtoo ah faa'iidooyinka caafimaad ee suurtagalka ah. Maqaalkani, waxaanu sahamin doonaa faa'iidooyinka kala duwan ee ginsenosides, oo ay ku jiraan saameyntooda shaqada garashada, habaynta habka difaaca jirka, sifooyinka anti-bararka, iyo dhaqdhaqaaqa ka hortagga kansarka ee suurtagalka ah.

Shaqada garashada

Mid ka mid ah faa'iidooyinka ugu caansan ee ginsenosides waa awooddooda si ay u hagaajiyaan shaqada garashada. Daraasado dhowr ah ayaa muujiyay in ginsenosides ay kor u qaadi karaan xusuusta, barashada, iyo guud ahaan waxqabadka garashada. Saamayntan waxaa loo maleynayaa in lagu dhexdhexaadiyo habab kala duwan, oo ay ku jiraan beddelka neurotransmitters, sida acetylcholine iyo dopamine, iyo kor u qaadida neurogenesis, habka soo saarida neerfayaasha cusub ee maskaxda.

Daraasad lagu daabacay joornaalka Ethnopharmacology, cilmi-baarayaashu waxay ogaadeen in ginsenosides ay hagaajin karaan barashada booska iyo xusuusta jiirka iyagoo kor u qaadaya muujinta maskaxda-derived neurotrophic factor (BDNF), borotiinka taageera badbaadada iyo koritaanka neerfayaasha. Intaa waxaa dheer, ginsenosides ayaa la muujiyay inay ka ilaalinayaan hoos u dhaca garashada ee da'da la xiriirta iyo cudurrada neurodegenerative, sida Alzheimers iyo Parkinson's disease, iyagoo yareynaya cadaadiska oksaydhka iyo bararka maskaxda.

Habaynta Nidaamka Difaaca

Ginsenosides ayaa sidoo kale lagu ogaadey inay wax ka beddesho habka difaaca jirka, kor u qaadida awoodda ay uga hortagto caabuqyada iyo cudurrada. Xeryahooda ayaa la muujiyey inay kiciyaan wax soo saarka iyo dhaqdhaqaaqa unugyada difaaca ee kala duwan, sida unugyada dilaaga dabiiciga ah, macrophages, iyo T lymphocytes, kuwaas oo door muhiim ah ka ciyaara difaaca jirka ee cudurada faafa iyo unugyada kansarka.

Daraasad lagu daabacay joornaalka caalamiga ah ee Immunopharmacology ayaa muujisay in ginsenosides ay kor u qaadi karto jawaabta difaaca ee jiirarka iyada oo kordhinaysa wax soo saarka cytokines, kuwaas oo tilmaamaya molecules kuwaas oo xakameynaya shaqada unugyada difaaca. Intaa waxaa dheer, ginsenosides ayaa lagu muujiyay inay leeyihiin guryaha ka hortagga fayraska iyo bakteeriyada, taas oo ka dhigaysa daaweyn dabiici ah oo rajo leh oo lagu taageerayo caafimaadka difaaca iyo ka hortagga caabuqyada.

Guryaha ka hortagga bararka

Caabuqa waa jawaab-celinta dabiiciga ah ee habka difaaca jirka ee dhaawaca iyo caabuqa, laakiin bararka dabadheeraadku wuxuu gacan ka geysan karaa horumarinta cudurro kala duwan, oo ay ku jiraan cudurrada wadnaha, sonkorowga, iyo kansarka. Ginsenosides ayaa lagu ogaadey inay leeyihiin sifooyin awood leh oo ka hortagga bararka, taas oo kaa caawin karta yaraynta saameynta waxyeellada leh ee bararka dabadheeraad ah ee jirka.

Daraasad lagu daabacay Joornaalka Cilmi-baarista Ginseng ayaa muujisay in ginsenosides ay xakameyn karto wax-soo-saarka cytokines-ka-bararka iyo xakameynta dhaqdhaqaaqa calaamadaha bararka ee unugyada difaaca. Intaa waxaa dheer, ginsenosides ayaa la muujiyay si loo yareeyo muujinta dhexdhexaadiyeyaasha bararka, sida cyclooxygenase-2 (COX-2) iyo nitric oxide synthase (iNOS), kuwaas oo ku lug leh jawaabta bararka.

Dhaqdhaqaaqa Ka hortagga Kansarka

Meel kale oo xiiso leh cilmi-baarista ginsenoside waa waxqabadkooda ka hortagga kansarka ee suurtagalka ah. Daraasado dhowr ah ayaa soo jeediyay in ginsenosides laga yaabo inay sameeyaan saameynaha kansarka ka hortagga kansarka iyadoo la xakameynayo koritaanka iyo bararka unugyada kansarka, taasoo keenaysa apoptosis (dhimashada unugyada barnaamijka), iyo xakameynta angiogenesis ee buro (sameynta xididdada dhiigga cusub si ay u taageeraan koritaanka burada).

Dib-u-eegis lagu daabacay joornaalka Caalamiga ah ee Sayniska Molecular ayaa iftiimiyay awoodda ka hortagga kansarka ee ginsenosides, gaar ahaan naasaha, sambabada, beerka, iyo kansarka mindhicirka. Dib-u-eegistu waxay ka hadashay hababka kala duwan ee ginsenosides ay sameeyaan saameyntooda ka hortagga kansarka, oo ay ku jiraan isbeddelka hababka calaamadaha unugyada, nidaaminta horumarka wareegga unugyada, iyo kor u qaadida jawaabta difaaca ee unugyada kansarka.

Gabagabo

Gebogebadii, ginsenosides waa xeryahooda bioactive ee laga helo Panax ginseng oo bixiya faa'iidooyin caafimaad oo ballaaran oo suurtagal ah. Kuwaas waxaa ka mid ah hagaajinta shaqada garashada, habaynta habka difaaca jirka, sifooyinka anti-bararka, iyo dhaqdhaqaaqa ka hortagga kansarka ee suurtagalka ah. Iyadoo cilmi-baaris dheeraad ah loo baahan yahay si loo fahmo hababka ficil-celinta iyo awoodda daaweynta ee ginsenosides, caddaynta hadda jirta waxay soo jeedinaysaa in xeryahooda ay ballanqaadayaan sida daawooyinka dabiiciga ah ee kor loogu qaadayo caafimaadka guud iyo fayoobaanta.

Tixraacyo
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 waxay xakameysaa firfircoonida unugyada dendritic iyo kororka unugyada T-ga ee vitro iyo in vivo. Immunopharmacology caalamiga, 17(3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology of ginsenosides: dib u eegista suugaanta. Daawooyinka Shiinaha, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Isticmaalka ginseng ee daawada iyadoo xoogga la saarayo xanuunada neurodegenerative. Joornaalka Sayniska Farmasiga, 100 (3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, oo ah istaraatiijiyad neuroprotective oo suurtagal ah. Kabista iyo Daawada Beddelka ah ee ku Salaysan Caddaynta, 2012.
Yuun, TK (2001). Hordhac kooban ee Panax ginseng CA Meyer. Joornaalka Sayniska Caafimaadka Kuuriya, 16 (Suppl), S3.


Waqtiga boostada: Abriil-16-2024
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