Hordhac:
Yamaaruggii caanaha, oo cilmi ahaan loo yaqaan Silybum marianum, ayaa loo aqoonsaday sifooyinka daweynta ee suurtagalka ah qarniyo badan. Caadi ahaan loo isticmaalo dawo dhaqameed, yamaaruggii caanaha ayaa hadda si weyn u soo jiidanaya bulshada sayniska. Markaad dhexda u gasho qaybta cilmi-baadhista ee hadda jirta, qoraalkan blog-ka ah ee dhammaystiran wuxuu ujeedkiisu yahay inuu sahamiyo faa'iidooyinka caafimaad ee ku salaysan sayniska ee loo aaneeyo yamaaruggii caanaha.
I. Fahamka Halabuurka Yamaaruggii caanaha: Silymarin: Isku-dhafka Xiddigaha
Yamaaruggii caanaha (Silybum marianum) waa geed ubaxeed u dhashay gobolka Mediterranean-ka waxaana qarniyo badan loo isticmaali jiray dawo dhaqameed. Mid ka mid ah xeryahooda firfircoon ee muhiimka ah ee laga helo yamaaruggii caanaha waa silymarin, isku dhafka kakan ee flavonolignans oo ay ku jiraanSilybin, silydianin, iyo silychristin. Silymarin waxay ugu horrayn ku urursan tahay miraha geedka yamaaruggii caanaha waxayna mas'uul ka tahay qaar badan oo ka mid ah faa'iidooyinka caafimaad ee suurtagalka ah.
Suurtogalnimada Antioxidant:
Doorka Silymarin ee ah antioxidant awood leh ayaa si weyn loo aqoonsan yahay. Waxay fulisaa saamaynta antioxidant iyada oo ka takhalusaysa xagjirrada xorta ah ee waxyeellada leh, molecules kuwaas oo u keeni kara dhaawaca unugyada. Xagjiriinta xorta ah waa wax soo saara hababka kala duwan ee jidhka, oo ay ku jiraan dheef-shiid kiimikaad iyo soo-gaadhista sunta deegaanka.
Cilmi baaris ayaa muujisay in silymarin ay si toos ah u baabi'in karto xagjirnimada xorta ah waxayna kor u qaadi kartaa waxqabadka enzymes-ka antioxidant-ka, sida superoxide dismutase (SOD) iyo glutathione peroxidase (GPx). Iyada oo la joojinayo soo saarista noocyada ogsijiinta falcelinta iyo dhimista cadaadiska oksaydhka, silymarin waxay ka caawisaa ka ilaalinta unugyada dhaawaca waxayna kor u qaadaysaa caafimaadka guud ee gacanta.
Saamaynta Ka-hortagga caabuqa:
Marka lagu daro sifooyinka antioxidant-ka, silymarin ayaa sidoo kale muujisay saameyno la taaban karo oo ka hortagga bararka. Caabuqa dabadheeraadku waxa uu la xidhiidhaa xaalado caafimaad oo kala duwan, oo ay ku jiraan cudurka beerka, macaanka, cudurrada wadnaha iyo xididdada dhiigga, iyo noocyada kansarka qaarkood. Guryaha anti-bararka ee Silymarin ayaa ka dhigaya musharax daaweyn soo jiidasho leh si loo maareeyo xaaladahan iyo kor u qaadida fayo-qabka guud.
Silymarin ayaa lagu muujiyay in ay joojiso muujinta dhexdhexaadiyeyaasha pro-inflammatory, sida buro necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), iyo factor factor-kappa B (NF-κB). Iyada oo wax ka beddeleysa arrimahan bararka, silymarin waxay kaa caawinaysaa yaraynta bararka waxayna yaraynaysaa dhaawaca unugyada.
Intaa waxaa dheer, saamaynta anti-bararka ee silymarin waxay kordhisaa saamaynta ay ku leedahay cadaadiska oksaydhka. Caabuqa dabadheeraadku wuxuu inta badan gacanta la socdaa cadaadiska oksaydhiyaha ee kordhay, iyo firfircoonida silymarin ee antioxidant-ka waxay caawisaa dhimista bararka waxyeelada oksaydhka.
Codsiyada daawaynta:
Astaamaha antioxidant-ka iyo anti-bararka ee silymarin waxay bixiyaan codsiyo daweyn oo suurtagal ah xaalado caafimaad oo kala duwan:
Caafimaadka Beerka: Silymarin waxaa si weyn loogu yaqaanaa saameynteeda hepatoprotective. Waxay ka ilaalin kartaa unugyada beerka waxyeellada ay keento sunta, cadaadiska oksaydhka, iyo bararka. Cilmi-baaristu waxay soo jeedinaysaa in silymarin ay gacan ka geysan karto hagaajinta shaqada beerka, kor u qaadida dib u soo kabashada beerka, iyo yaraynta cudurrada beerka sida cagaarshow, cudur beerka dufan leh, iyo cirrhosis.
Maareynta Sonkorowga:
Silymarin waxay muujisay saameyn rajo leh oo lagu maareynayo cudurka macaanka iyadoo hagaajinaysa dareenka insulin iyo hoos u dhigista heerarka sonkorta dhiigga. Intaa waxaa dheer, waxay kaa caawin kartaa inaad ka ilaaliso unugyada beta ee ganaca, kuwaas oo ka masuul ah soo saarista insulinta, waxyeelada oksaydhka iyo hababka bararka.
Caafimaadka Wadnaha:
Antioxidant-ka iyo sifooyinka ka-hortagga bararka ee silymarin waxay faa'iido u yeelan karaan ilaalinta caafimaadka wadnaha. Iyada oo la dhimayo cadaadiska oksaydhiyaha iyo bararka, silymarin waxay kaa caawin kartaa ka hortagga atherosclerosis, yaraynta cadaadiska dhiigga, iyo hagaajinta astaamaha dufanka.
Kahortagga Kansarka:
Antioxidant-ka xoogga leh iyo saamaynta ka-hortagga bararka ee silymarin ayaa laga yaabaa inay gacan ka geysato awooddeeda wakiilka ka-hortagga kansarka. Daraasaduhu waxay muujiyeen in silymarin ay carqaladeyn karto kororka unugyada kansarka, ay keento apoptosis (dhimashada unugyada qorshaysan) ee unugyada kansarka, iyo in ay joojiso korriinka burooyinka dhowr nooc oo kansar ah, oo ay ku jiraan naasaha, qanjirka 'prostate', iyo kansarka mindhicirka.
Gebagebadii, silymarin, oo ah isku dhafka xiddigaha laga helo yamaaruggii caanaha, ayaa bixiya faa'iidooyin caafimaad oo kala duwan. Waxyaabaha ay ka kooban tahay antioxidant-ka ayaa unugyada ka ilaaliya dhaawaca oksaydhka, halka saameynteeda anti-bararka ay ka caawiso dhimista bararka iyo dhibaatooyinka la xiriira. Cilmi-baaris dheeraad ah ayaa lagama maarmaan u ah in si buuxda loo fahmo hababka ficilka iyo codsiyada daaweynta ee suurtogalka ah ee silymarin, laakiin caddaynta hadda jirta waxay soo jeedinaysaa doorkeeda rajo-gelinta ah ee kor u qaadida fayo-qabka guud iyo ka hortagga xaalado caafimaad oo kala duwan.
II. Soo Bandhigidda Faa'iidooyinka Yamaaruggii Caanaha:
1. Caafimaadka Beerka iyo Sun-saarista:
Yamaaruggii caanuhu wuxuu leeyahay taariikh dheer oo loo isticmaalo horumarinta caafimaadka beerka iyo taageeridda hababka sun-saarista. Qarniyadii oo dhan, waxaa loo aqoonsaday sifooyinka hepatoprotective iyo awoodda ay u leedahay inay ka caawiso dib u soo kabashada unugyada beerka.
Cilmi-baadhis cilmiyeed ayaa bixisay caddayn lagu taageerayo isticmaalka dhaqameed ee yamaaruggii caanaha ee caafimaadka beerka. Silymarin, oo ah xarunta ugu weyn ee firfircoon ee yamaaruggii caanaha, ayaa lagu muujiyay inay leedahay antioxidant iyo saamaynta anti-bararka, taas oo ka caawin karta ilaalinta unugyada beerka dhaawaca ay keento sunta iyo xagjirrada xorta ah. Silymarin sidoo kale waxay kicisaa dib u soo kabashada unugyada beerka, caawinta hagaajinta unugyada beerka.
Intaa waxaa dheer, yamaaruggii caanaha ayaa la ogaaday in ay xoojiso hababka sun-saarista beerka. Waxay taageertaa dhaqdhaqaaqa enzymes ee ku lug leh Wajiga I iyo Wajiga II ee dariiqyada sun-saarista beerka, taas oo ka caawisa jirka inuu si hufan u baabi'iyo sunta iyo walxaha waxyeellada leh. Kor u qaadida sun-saarista beerka, yamaaruggii caanaha ayaa laga yaabaa inay ka hortagaan ururinta sunta waxayna yareeyaan halista dhaawaca beerka.
2. Cudurada Beerka: Cirrhosis iyo Cagaarshowga:
Cirrhosis iyo cagaarshow waa xaalado beerka raaga oo cawaaqib xun ku yeelan kara caafimaadka guud. Yamaaruggii caanaha ayaa muujiyay ballan lagu maareynayo xaaladahan iyo taageerida caafimaadka beerka.
Daraasadaha kiliinikada ayaa baadhay waxtarka yamaaruggii caanaha ee cirrhosis iyo daaweynta cagaarshow. Cilmi-baaristu waxay soo jeedinaysaa in caanaha yamaarugirka caanaha laga yaabo inay gacan ka geystaan hagaajinta shaqada beerka ee shakhsiyaadka qaba cirrhosis iyagoo yareynaya bararka, kor u qaadista dib u soo kabashada unugyada beerka, iyo kor u qaadista hababka sunta. Waxa kale oo laga yaabaa inay kaa caawiso yaraynta calaamadaha sida daalka iyo dhibaatooyinka beerka la xiriira.
Sidoo kale, yamaaruggii caanaha ayaa muujiyay faa'iidooyinka suurtagalka ah ee shakhsiyaadka qaba cagaarshow, oo ay ku jiraan cagaarshow fayras ah. Daraasaduhu waxay muujiyeen in yamaaruggii caanaha ay kaa caawin karaan dhimista bararka beerka, caadiyeynta heerarka enzyme beerka, iyo hagaajinta guud ahaan caafimaadka beerka. Si kastaba ha ahaatee, cilmi baaris dheeraad ah ayaa loo baahan yahay si loo go'aamiyo qiyaasta ugu fiican iyo muddada daaweynta ee yamaaruggii caanaha ee xaaladahan.
3. Kahortagga iyo Daaweynta Kansarka:
Daraasado hore oo caafimaad ayaa iftiimiyay yamaaruggii caanaha sifooyinka suurtagalka ah ee ka hortagga kansarka, iyagoo soo jeedinaya inay faa'iido u leedahay ka hortagga iyo daaweynta kansarka.
Xeryahooda firfircoon ee yamaaruggii caanaha, gaar ahaan silymarin, ayaa la ogaaday inay soo bandhigaan saamaynta kansarka ka hortagga kansarka ee daraasado kala duwan oo hore. Waxay muujiyeen awoodda ay u leeyihiin inay joojiyaan koritaanka unugyada kansarka oo ay ka hortagaan faafitaankooda (metastasis). Silymarin ayaa sidoo kale la ogaaday in ay wax ka beddesho dariiqyada calaamadaha ee ku lug leh horumarka kansarka, taas oo suurtogal ah in ay yareyso khatarta abuuritaanka burada.
Si kastaba ha ahaatee, waxaa muhiim ah in la ogaado in inta badan daraasaddan lagu sameeyay goobaha shaybaadhka ama xayawaanka. Baadhitaano caafimaad oo dheeraad ah ayaa lagama maarmaan u ah in la dhiso yamaaruggii caanaha sidii ikhtiyaar daawaynta kansarka oo macquul ah iyo in la go'aamiyo qiyaasta ku habboon iyo borotokoolka daaweynta.
4. Maareynta Sonkorowga:
Yamaaruggii caanaha ayaa loo sahamiyay doorka ay ku yeelan karto hagaajinta xakamaynta sonkorta dhiigga iyo iska caabbinta insulinta, taasoo ka dhigaysa daawaynta isku xidhka ee maaraynta sonkorowga.
Cilmi-baaristu waxay soo jeedinaysaa in xeryahooda firfircoon ee yamaaruggii caanaha, sida silymarin, laga yaabo inay gacan ka geystaan nidaaminta heerarka sonkorta dhiigga iyagoo kor u qaadaya dareenka insulinta iyo yaraynta caabbinta insulinta. Silymarin ayaa la ogaaday inay hagaajiso dheef-shiid kiimikaadka gulukooska, hoos u dhigida heerarka sonkorta dhiigga ee soonka, iyo hoos u dhigista calaamadaha caabbinta insulin ee xayawaanka iyo daraasadaha aadanaha.
Sahaminta dheeraadka ah ee xeryahooda firfircoon ee ku jira yamaaruggii caanaha, oo ay ku jiraan hababka ay wax u qabtaan, ayaa laga yaabaa inay bixiso fikrado ku saabsan saameynteeda ka hortagga sonkorowga. Tijaabooyin caafimaad ayaa lagama maarmaan u ah si loo xaqiijiyo waxtarka yamaaruggii caanaha sida daawaynta dhammaystirka ah ee maaraynta sonkorowga iyo in la aqoonsado qiyaasta ugu fiican iyo muddada daaweynta.
5. Caafimaadka dheefshiidka:
Yamaaruggii caanaha ayaa sidoo kale laga yaabaa inay saameyn togan ku yeeshaan caafimaadka dheefshiidka, gaar ahaan yareynta dheef-shiidka iyo calaamadaha la xiriira cilladda mindhicirka xanaaqa (IBS).
Daraasaduhu waxay soo jeedinayaan in yamaaruggii caanuhu sifooyinka anti-bararka iyo antioxidant-ka ay gacan ka geystaan faa'iidooyinka suurtagalka ah ee cudurrada dheefshiidka. Marka la yareeyo bararka habka dheef-shiidka, yamaaruggii caanaha ayaa laga yaabaa inay kaa caawiyaan yareynta calaamadaha dheef-shiidka, sida bararka, gaaska, iyo raaxo-darrada caloosha. Intaa waxaa dheer, awoodda ay u leedahay in ay taageerto microbiome mindhicirka caafimaadka qaba ayaa laga yaabaa inay gacan ka geysato hagaajinta shaqada dheef-shiidka iyo yaraynta calaamadaha la xidhiidha IBS.
6. Yamaaruggii caanaha ayaa difaaci kara lafahaaga:
Daraasado horudhac ah ayaa tilmaamay doorka suurtagalka ah ee yamaaruggii caanaha si kor loogu qaado caafimaadka lafaha. Silymarin ayaa la ogaaday in ay kiciso samaynta lafaha oo ay joojiso luminta lafaha daraasadaha xayawaanka. Cilmi baaris dheeraad ah ayaa loo baahan yahay si loo sahamiyo saameynta ay yamaaruggii caanaha ku leeyihiin caafimaadka lafaha ee bini'aadamka iyo go'aaminta kartida ay u leedahay habka daaweynta xaaladaha sida lafo-jileeca.
7. Waxa laga yaabaa inay caawiso ka hortagga hoos u dhaca da'da ee la xidhiidha shaqada maskaxda:
Cilmi-baaris soo ifbaxday waxay soo jeedinaysaa in yamaaruggii caanaha laga yaabo inay saameyn faa'iido leh ku yeeshaan caafimaadka maskaxda oo laga yaabo inay ka hortagaan hoos u dhaca garaadka da'da. Daraasado horudhac ah ayaa muujiyay in laga soosaaray yamaaruggii caanuhu ay ka ilaalin karaan cadaadiska oksaydhka iyo in ay yareeyaan bararka maskaxda, kuwaas oo ah qodobbada muhiimka ah ee la xidhiidha hoos u dhaca garashada da'da iyo cudurrada neurodegenerative sida Alzheimers. Cilmi baaris dheeraad ah, oo ay ku jiraan tijaabooyin caafimaad, ayaa loo baahan yahay si si buuxda loo sahamiyo faa'iidooyinka suurtagalka ah ee yamaaruggii caanaha ee caafimaadka maskaxda.
8. Waxay Kori Kartaa Soosaarka Caanaha Naaska:
Dhaqan ahaan, yamaaruggii caanaha ayaa loo isticmaali jiray galactagogue, walax kor u qaada soosaarka caanaha naaska. Iyadoo cilmi-baaris dheeraad ah loo baahan yahay, cilmi-baarisyada qaarkood waxay soo jeedinayaan in yamaaruggii caanaha laga yaabo inay gacan ka geystaan kordhinta wax soo saarka caanaha haweenka naaska nuujiya. Si kastaba ha ahaatee, waa lagama maarmaan inaad la tashato xirfadle daryeel caafimaad ka hor inta aanad u isticmaalin yamaaruggii caanaha ujeedadan.
Gebogebadii, yamaaruggii caanuhu wuxuu bixiyaa faa'iidooyin caafimaad oo kala duwan oo ay taageerto cilmi-baaris cilmiyeed. Laga soo bilaabo caafimaadka beerka iyo sun-saarista ilaa doorarka suurtagalka ah ee ka hortagga kansarka, maaraynta sonkorowga, caafimaadka dheefshiidka, iyo xitaa caafimaadka lafaha iyo shaqada maskaxda, yamaaruggii caanaha ayaa sii ahaanaya mawduuc cilmi baaris ah. Si kastaba ha ahaatee, cilmi-baaris dheeraad ah, oo ay ku jiraan tijaabooyin caafimaad oo si fiican loo qaabeeyey, ayaa lagama maarmaan u ah in la dhiso qiyaaso gaar ah, borotokoolka daaweynta, iyo waxtarka guud ee dadweynaha kala duwan ee codsiyada caafimaadka kala duwan ee yamaaruggii caanaha.
III. Soo Bandhigidda Farsamooyinka Ka Danbaysa Faa'iidooyinka Yamaaruggii Caano:
Habaynta Enzymes iyo Calaamadaynta Unugyada:
Yamaaruggii caanaha, cilmi ahaan loo yaqaan Silybum marianum, waxaa ku jira xeryahooda bioactive sida silymarin, silybin, iyo flavonoids kale oo door muhiim ah ka ciyaara saameyntiisa faa'iido leh. Iskudhisyadan ayaa si weyn loo daraaseeyay awooddooda ay ku beddelaan enzymes iyo dariiqyada calaamadaha gacanta.
Enzymes ayaa muhiim u ah hababka kala duwan ee jireed ee jirka, oo ay ku jiraan dheef-shiid kiimikaad, sun-saarid, iyo homeostasis-ka gacanta. Xeryahooda yamaaruggii caanaha ayaa la ogaaday inay la falgalaan dhowr enzymes oo muhiim ah, taasoo keentay natiijooyin wanaagsan. Tusaale ahaan, silymarin waxay muujisay saameyn lid ku ah cytochrome P450 enzymes, kuwaas oo ku lug leh dheef-shiid kiimikaadka daroogada, taas oo yaraynaysa khatarta sunta beerka ee daroogada.
Intaa waxaa dheer, xeryahooda yamaaruggii caanaha ayaa muujiyay awoodda ay ku beddelaan dariiqyada calaamadaha unugyada. Mid ka mid ah dariiqa calaamadaynta ee caanka ah ee ay saameeyeen yamaaruggii caanaha ayaa ah habka nukliyeerka ee kappa B (NF-κB), kaas oo xakameynaya muujinta gen ee ku lug leh caabuqa iyo jawaabaha difaaca. Silymarin ayaa lagu muujiyay in ay joojiso firfircoonida NF-κB, taasoo keentay hoos u dhac ku yimaada cytokines pro-inflammatory iyo muujinta enzymes ee ku lug leh bararka, ugu dambeyntii hoos u dhigista bararka iyo ilaalinta guriga homeostasis.
Waxaa intaa dheer, yamaaruggii caanaha ayaa la ogaaday inay saameyn ku yeeshaan muujinta iyo waxqabadka enzymes kale oo kala duwan oo ku lug leh hababka difaaca antioxidant. Enzymes-yadan waxaa ka mid ah superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx), iyo glutathione reductase. Marka la wanaajiyo waxqabadka enzymes-kan, yamaaruggii caanaha ayaa ka caawiya la dagaallanka diiqada oksaydhka iyo saamaynta xun ee ay ku leedahay caafimaadka gacanta.
Kahortagga Cadaadiska Oxidative:
Cadaadiska Oxidative wuxuu dhacaa marka ay jirto isku dheelitir la'aan udhaxeysa soosaarka noocyada ogsijiinta falcelinta (ROS) iyo hababka difaaca jirka ee antioxidant-ka. Waxay ku lug leedahay cudurro badan oo daba-dheeraada iyo gabowga oo la dedejiyo. Kartida yamaaruggii caanaha si ay uga hortagaan diiqada oksaydhisku waxay ku jirtaa maadada hodanka ah ee xeryahooda antioxidant, gaar ahaan silymarin.
Silymarin, oo ah qaybta ugu wanaagsan ee si fiican loo bartay ee yamaaruggii caanaha, ayaa la muujiyay in ay leedahay sifooyin antioxidant awood leh. Waxay u shaqeysaa sidii xagjirnimo xor ah, ka takhalusta ROS waxayna ka hortagtaa waxyeelada oksaydhiyaha ee qaab-dhismeedka gacanta iyo molecules, sida lipids, borotiinnada, iyo DNA-da. Iyaga oo unugyada ka ilaalinaya dhaawaca oksaydhiyaha, yamaaruggii caanaha ayaa ka caawiya ilaalinta daacadnimadooda, shaqadooda, iyo guud ahaan caafimaadka.
Intaa waxaa dheer, saamaynta antioxidant ee yamaaruggii caanuhu waxay dhaafsiisan tahay in si toos ah loo xoqo xagjirrada xorta ah. Silymarin ayaa la ogaaday in ay kiciso isku-darka iyo dhaqdhaqaaqa antioxidant-ka intracellular, oo ay ku jiraan glutathione, mid ka mid ah antioxidants ugu muhiimsan ee jirka. Kordhinta heerarka glutathione waxay kor u qaadaysaa nidaamka difaaca gacanta ee ka hortagga cadaadiska oksaydhka, xoojinta saamaynta ilaalinta ee yamaaruggii caanaha.
Marka laga soo tago saamaynta tooska ah ee antioxidant-ka, yamaaruggii caanaha ayaa lagu muujiyay in ay joojiso lipid peroxidation, habka wax u dhimaya xuubka unugyada isla markaana gacan ka geysta horumarinta cudurro kala duwan. Iyagoo ka hortagaya oksaydheynta xuubka, yamaaruggii caanaha ayaa ka caawiya ilaalinta daacadnimada xuubka waxayna yareeyaan halista cilladda gacanta.
Taageerada Nidaamka Difaaca:
Yamaaruggii caanaha ayaa sidoo kale la baaray awooddeeda lagu taageerayo laguna beddelo habka difaaca jirka, taasoo kor u qaadeysa hababka difaaca jirka ee cudurrada faafa iyo cudurrada.
Daraasado kala duwan ayaa soo jeediyay in xeryahooda yamaaruggii caanaha, gaar ahaan silymarin, ay muujiyaan sifooyin xoojiya difaaca jirka. Silymarin waxaa la ogaaday in ay kiciso soo saarida unugyada difaaca jirka, sida lymphocytes iyo macrophages, kuwaas oo door muhiim ah ka ciyaara jawaabta difaaca iyo ka hortagga caabuqyada. Xeryahooda ayaa sidoo kale muujiyay awoodda kor loogu qaado waxqabadka unugyada dilaaga dabiiciga ah (NK), kuwaas oo lagama maarmaan u ah difaaca unugyada kansarka iyo fayrasyada.
Waxaa intaa dheer, yamaaruggii caanaha ayaa lala xiriiriyay hoos u dhaca cytokines pro-bararka, sida buro necrosis factor-alpha (TNF-a) iyo interleukin-6 (IL-6). Iyadoo la joojinayo soo saarista cytokines-ka-bararka, yamaaruggii caanuhu wuxuu caawiyaa nidaaminta jawaabaha difaaca iyo ka hortagga bararka xad-dhaafka ah, kor u qaadida habka difaaca jirka oo dheellitiran.
Intaa waxaa dheer, yamaaruggii caanaha ayaa muujiyay saamaynta immunomodulatory by saamaynta shaqada unugyada difaaca. Tusaale ahaan, waxaa la ogaaday in ay kor u qaaddo dhaqdhaqaaqa phagocytic ee macrophages, hagaajinta awoodda ay u leeyihiin in ay baabi'iyaan cudurada. Xeryahooda yamaaruggii caanaha ayaa sidoo kale la muujiyay inay nidaamiyaan soo saarista unugyada difaaca gaarka ah, sida interferon-gamma (IFN-γ), kaas oo door muhiim ah ka ciyaara difaaca fayraska iyo bakteeriyada.
Guud ahaan, awoodda yamaaruggii caanaha si ay wax uga beddelaan enzymes, saameyn ku yeeshaan waddooyinka calaamadaynta unugyada, ka hortagga cadaadiska oksaydhka, iyo taageeridda habka difaaca ayaa gacan ka geysta faa'iidooyinka kala duwan ee kala duwan. Iyadoo cilmi baaris dheeraad ah loo baahan yahay si loo fahmo hababka adag ee ka hooseeya saamaynta yamaaruggii caanaha, caddaynta sayniska ee hadda jirta waxay muujineysaa awooddeeda sida wakiilka dabiiciga ah ee horumarinta caafimaadka iyo fayoobaanta.
IV. Xaqiijinta Isticmaalka Badbaado iyo Wax ku ool ah:
Qiyaasta iyo Maamulka:
Markaad tixgelinayso isticmaalka yamaaruggii caanaha sidii kabitaan ama daawo dhireed, waxaa muhiim ah inaad raacdo tilmaamaha qiyaasta ku habboon sida ay dejiyeen caddaynta sayniska iyo fikradaha khabiirada. Qiyaasta lagu taliyey ee yamaaruggii caanaha way kala duwanaan kartaa iyadoo ku xiran nooca gaarka ah ee badeecada, sida soosaarayaasha caadiga ah, kaabsal, ama tinctures.
Iyada oo ku saleysan suugaanta sayniska ee la heli karo, kala duwanaanta qiyaasta caadiga ah ee soosaarka yamaaruggii caanaha oo lagu qiyaaso inay ka kooban tahay 70-80% silymarin waa qiyaastii 200-400 mg oo la qaato laba ilaa saddex jeer maalintii. Waxaa guud ahaan la soo jeediyay in la qaato cunto yamaaruggii caanaha ah si kor loogu qaado nuugista. Si kastaba ha ahaatee, waa muhiim in dib loo eego tilmaamaha calaamadda gaarka ah oo lala tashado xirfadle daryeel caafimaad ama daaweeyaha talooyinka gaarka ah.
Waxaa xusid mudan in baahiyaha gaarka ah iyo xaaladaha caafimaad ay kala duwanaan karaan, la-talinta xirfadlaha daryeelka caafimaadka ayaa had iyo jeer lagula talinayaa si loo go'aamiyo qiyaasta ku habboon baahida gaarka ah ee qof kasta.
Saamaynnada iyo Is-dhexgalka suurtagalka ah:
Iyadoo yamaaruggii caanaha guud ahaan loo tixgeliyo inay badbaado u tahay shakhsiyaadka intooda badan marka la qaato qiyaasta ku habboon, waxaa muhiim ah in la ogaado waxyeellooyinka iyo isdhexgalka ka iman kara isticmaalka.
Shakhsiyaadka qaarkood waxay la kulmi karaan khalkhal fudud oo caloosha ah, sida shuban, dibiro, ama calool xanuun. Saamayntan inta badan waa naadir waana ku meel gaadh. Haddii calaamadahan oo kale dhacaan, waxaa laga yaabaa inay caqli gal tahay in la yareeyo qiyaasta si ku meel gaar ah ama la joojiyo isticmaalka ilaa lagala tashanayo xirfadle daryeel caafimaad.
Marka laga hadlayo isdhexgalka daawooyinka, yamaaruggii caanaha ayaa awood u leh in ay la falgalaan daawooyinka qaarkood sababtoo ah saameynta ay ku leedahay enzymes dheef-shiid kiimikaadka daroogada ee beerka. Gaar ahaan, waxay saameyn kartaa waxqabadka cytochrome P450 enzymes, kuwaas oo mas'uul ka ah dheef-shiid kiimikaad daawooyin badan.
Yamaaruggii caanaha ayaa laga yaabaa inay xannibaan enzymes-kan, taasoo keenta heerarka dhiigga ee daawooyinka qaarkood oo ay suurtogal tahay inay beddelaan waxtarkooda ama ay keenaan saameyn xun. Tusaalooyinka qaar ee daawooyinka laga yaabo in ay la falgalaan yamaaruggii caanaha waxaa ka mid ah statins, anticoagulants, antiplatelet drugs, daawooyinka ka hortagga sonkorowga, iyo daawooyinka dhimirka qaarkood.
Si loo hubiyo in ay si badbaado leh u dhexgalaan yamaaruggii caanaha ee qorshayaasha daawaynta ee jira, waxaa muhiim ah in lala tashado xirfadle daryeel caafimaad, gaar ahaan haddii daawooyinka qaarkood si isku mid ah loo qaato. Waxay bixin karaan hagitaan shakhsi ahaaneed waxayna hagaajin karaan qiyaasta daawada haddii loo baahdo si loo waafajiyo isdhexgalka suurtagalka ah.
Iyadoo yamaaruggii caanaha guud ahaan loo aqoonsan yahay inay badbaado yihiin, waxaa lagama maarmaan ah in la tixgeliyo arrimaha caafimaadka shakhsi ahaaneed, taariikhda caafimaadka, iyo daaweynta socota. Haweenka uurka leh ama naaska nuujinaya, shakhsiyaadka leh xaalado caafimaad oo hoose, ama kuwa loo qorsheeyay qalliinka waa inay sameeyaan taxadar oo ay la tashadaan xirfadle daryeel caafimaad ka hor intaysan bilaabin wax kabitaan ah oo cusub.
Gebogebadii, yamaaruggii caanuhu waxay bixin karaan faa'iidooyin sayniska ku salaysan oo kala duwan, laakiin hubinta isticmaalka badbaadada iyo waxtarka leh waxay u baahan tahay fiiro gaar ah qiyaasta ku habboon, tilmaamaha maamulka, iyo dhibaatooyinka iman kara iyo isdhexgalka. Markaad raacdo tilmaamaha lagu taliyay, raadinta talo-yaqaannada, iyo la socodka jawaabta qofka ee yamaaruggii caanaha, shakhsiyaadka waxay kordhin karaan faa'iidooyinka caafimaad ee suurtagalka ah iyagoo yareynaya khatar kasta oo iman karta.
Gabagabo:
Daawooyinka dabiiciga ah, yamaaruggii caanuhu waxay u taagan yihiin inay yihiin awood ka iman karta faa'iidooyinka caafimaadka. Iyadoo qaybta cilmi-baarista ee jirta ay soo jeedinayso saameyn rajo leh, daraasado kale oo si fiican loo naqshadeeyey ayaa lagama maarmaan u ah in la dhiso waxtarka yamaaruggii caanaha si dhammaystiran. Markaad iftiimiso faa'iidooyinka sayniska ku salaysan ee yamaaruggii caanaha, qoraalkan blog-ka ah ee dhamaystiran wuxuu u adeegaa kheyraad qiimo leh oo loogu talagalay shakhsiyaadka raadinaya aqoon ku salaysan caddaynta si ay u sameeyaan go'aamo xog-ogaal ah oo ku saabsan ku darista yamaaruggii caanaha ee caadooyinkooda fayoobida. Xasuusnoow, had iyo jeer kala tasho xirfadlayaasha daryeelka caafimaadka talo shakhsiyeed ka hor inta aanad bilaabin wax daaweyn ah ama kaabis ah.
Nala soo xidhiidh:
Grace HU (Maareeyaha Suuqgeynta)grace@biowaycn.com
Carl Cheng (Maamule/Maamule)ceo@biowaycn.com
Mareegta:www.biowaynutrition.com
Waqtiga boostada: Oct-31-2023
